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Troparil, also known by its chemical names (–)-2β-Carbomethoxy-3β-phenyltropane, WIN 35,065-2, or β-CPT, is a synthetic stimulant compound with a unique profile in the world of pharmacology. It is a potent dopamine reuptake inhibitor that has garnered interest for both its scientific applications and potential therapeutic uses.
When you seek to understand Troparil, you’re diving into the realm of stimulant compounds with significant implications in medical research and potential therapeutic applications. This comprehensive guide will help you navigate through the complexities of Troparil, from its chemical structure to its potential uses.
Key Takeaways:
- Troparil is a synthetic stimulant.
- Known for its dopamine reuptake inhibition properties.
- Investigated for medical and therapeutic applications.
Synonyms
|
WIN 35,065-2 or β-CPT |
IUPAC
|
(–)-2β-Carbomethoxy-3β-phenyltropane |
Formula
|
C16H21NO2 |
Molecular weight
|
259.343 g/mol |
CAS
|
74163-84-1 |
Appearance
|
White Powder |
Purity
|
≥ 98% |
Restriction
|
Regulated |
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Troparil and all the other designer products sold on this website are designed for research and forensic work.
Chemical Structure of Troparil
The chemical structure of Troparil sets it apart from other stimulant compounds. Structurally, it is closely related to cocaine but with modifications that enhance its stability and potency.
Key Points:
- Chemical Name: (–)-2β-Carbomethoxy-3β-phenyltropane.
- Formula: C16H19NO2.
- Related Compounds: Structurally similar to cocaine.
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Troparil’s unique structure enhances its pharmacological properties, making it a subject of extensive research.
Mechanism of Action of Troparil
Troparil primarily functions as a dopamine reuptake inhibitor. By blocking the dopamine transporter, it increases the concentration of dopamine in the synaptic cleft, leading to enhanced dopaminergic activity.
Key Points:
- Inhibition: Dopamine reuptake inhibitor.
- Effect: Increases synaptic dopamine levels.
- Implication: Enhanced mood and cognitive functions.
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The mechanism of Troparil involves increasing dopamine levels, which can enhance mood and cognitive abilities.
Potential Medical Uses
The potential medical uses of Troparil are diverse, ranging from treatments for neurodegenerative diseases to attention deficit hyperactivity disorder (ADHD).
Key Points:
- Neurodegenerative Diseases: Potential in Parkinson’s disease.
- ADHD: Could serve as an alternative to traditional stimulants.
- Depression: Investigated for treatment-resistant depression.
Comparison with Other Stimulants
When comparing Troparil with other stimulants like cocaine, methamphetamine, and methylphenidate, it shows distinct advantages and differences.
Stimulant | Dopamine Inhibition | Addiction Potential | Therapeutic Use |
---|---|---|---|
Troparil | High | Lower | Research in neurodegenerative diseases, ADHD |
Cocaine | High | High | Limited medical use |
Methamphetamine | Very High | Very High | ADHD, obesity |
Methylphenidate | Moderate | Moderate | ADHD, narcolepsy |
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Troparil stands out with its lower addiction potential and promising therapeutic applications compared to other stimulants.
Legal Status and Availability
Understanding the legal status and availability of Troparil is crucial for researchers and medical professionals.
Key Points:
- Controlled Substance: Classified in many regions.
- Research Chemical: Primarily available for scientific research.
- Regulatory Status: Varies by country.
Summary:
Troparil is generally controlled and primarily available for research purposes.
Safety and Side Effects
Safety and side effects are paramount when considering any stimulant. Troparil’s profile suggests some common stimulant side effects, with particular attention needed for its long-term impact.
Key Points:
- Common Side Effects: Insomnia, anxiety, increased heart rate.
- Long-term Effects: Potential neurotoxicity with prolonged use.
- Safety: Requires careful monitoring.
Summary:
While Troparil shares common stimulant side effects, its long-term safety profile necessitates careful study.
Research and Clinical Studies
Current research and clinical studies on Troparil are exploring its efficacy and safety across various applications.
Key Points:
- Current Studies: Focus on neurodegenerative diseases and ADHD.
- Preclinical Research: Ongoing animal studies.
- Clinical Trials: Limited but increasing.
Usage and Dosage Guidelines
For those involved in research, understanding the usage and dosage guidelines of Troparil is essential.
Key Points:
- Administration: Typically oral or intravenous.
- Dosage: Varies widely based on study and application.
- Guidelines: Strict adherence to research protocols.
Summary:
Proper usage and dosage of Troparil are crucial for ensuring safety and efficacy in research settings.
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The prospects of Troparil in medicine and research are exciting, with potential breakthroughs on the horizon.
Key Points:
- Therapeutic Applications: Expanding potential in various fields.
- Innovative Research: Ongoing studies could unlock new uses.
- Regulatory Approvals: Awaiting more data for wider medical use.
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The future of Troparil looks promising, with potential applications extending across various medical fields.
References
- Troparil and Dopamine Reuptake
- Medical Applications of Troparil
- Comparative Study of Stimulants
- Current Clinical Trials on Troparil
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1. What is Troparil used for?
Troparil is primarily used in research to study its effects on dopamine reuptake and potential therapeutic applications for conditions like ADHD and neurodegenerative diseases.
2. How does Troparil compare to cocaine?
Troparil and cocaine both inhibit dopamine reuptake, but Troparil is structurally modified to be less addictive and more stable for research purposes.
3. Is Troparil legal?
The legal status of Troparil varies by country. It is generally classified as a controlled substance and is mainly available for scientific research.
4. What are the side effects of Troparil?
Common side effects include insomnia, anxiety, and increased heart rate. Long-term use may pose risks of neurotoxicity.
5. Can Troparil be used to treat depression?
Troparil is being investigated for treatment-resistant depression due to its potent dopamine reuptake inhibition properties.
6. What is the chemical structure of Troparil?
Troparil is a synthetic stimulant with the chemical name (–)-2β-Carbomethoxy-3β-phenyltropane, structurally related to cocaine but with modifications.
7. How is Troparil administered in research?
Troparil can be administered orally or intravenously, depending on the research protocol.
8. What prospects does Troparil hold?
The future of Troparil includes potential therapeutic applications for a variety of medical conditions, pending further research and clinical trials.