What Is 2-FDCK? A Comprehensive Guide to 2-Fluorodeschloroketamine

2-FDCK, or 2-Fluorodeschloroketamine, is a research chemical that has steadily captured the interest of both the scientific community and forensic experts. Structurally akin to ketamine, 2-FDCK is part of the arylcyclohexylamine family—a class of dissociative agents known for their ability to induce sensory detachment and altered perception. While its recreational use remains a concern in several regions, 2-FDCK is primarily explored in controlled laboratory settings.

What is 2-FDCK? (2-Fluorodeschloroketamine)

2-FDCK is a synthetic dissociative anesthetic structurally related to ketamine, a Schedule III drug in the U.S. used medically for anesthesia and, more recently, depression. The “2-Fluoro” in its name refers to a fluorine atom added to ketamine’s core structure, a modification that subtly alters its effects and potency. Unlike ketamine, which has decades of clinical research behind it, 2-FDCK exists in a legal and scientific gray area. It’s part of a growing family of novel psychoactive substances (NPS) designed to mimic controlled drugs while avoiding regulation.

For a detailed look at its chemical profile, the National Center for Biotechnology Information provides a breakdown of 2-FDCK’s molecular structure. 2-FDCK belongs to the arylcyclohexylamine class. It is a derivative of ketamine, a well-known anesthetic used in medical and veterinary settings. 2-FDCK for sale .

For those seeking detailed chemical data, the PubChem entry provides a comprehensive overview of its molecular structure and properties.

Table 1. Key Chemical and Pharmacological Attributes of 2-FDCK

Attribute	Details
Chemical Name	2-(2-Fluorophenyl)-2-methylamino-cyclohexanone
Class	Arylcyclohexylamine (Dissociative)
Molecular Formula	C₁₃H₁₆FNO
Molecular Weight	221.27 g/mol
Mechanism of Action	NMDA receptor antagonist
Duration	2.5–5 hours (oral), 1.5–3 hours (insufflated)
Legal Status	Controlled in several countries (e.g., Italy)

This table offers a snapshot for quick reference and helps clarify where 2-FDCK stands in terms of both chemistry and its effects on the brain.

Chemical Properties of 2-FDCK

2-Fluorodeschloroketamine is classified as a dissociative anesthetic, belonging to the arylcyclohexylamine class of drugs. Chemically, it is a derivative of ketamine, with the chlorine atom in the phenyl ring replaced by a fluorine atom. This substitution alters its pharmacological properties, resulting in a slightly different experience compared to ketamine. 3-MMC crystal

Effects of 2-FDCK (2-Fluorodeschloroketamine)

Depending on the dosage, mode of administration, and individual circumstances, 2-FDCK might have different effects. As a dissociative anesthetic, it causes a person to become detached from their environment, which modifies perceptions and creates a detached feeling.

• Euphoria and relaxation
• Distorted sensory perception
• Dissociation from the body
• Hallucinations and visual distortions
• Increased introspection and self-reflection

Potential Uses

• Research purposes: Primarily used as a research chemical by scientists and researchers in various fields. Its unique properties make it a valuable tool for studying the mechanisms of dissociative anesthetics and exploring potential therapeutic applications.
• Recreational use: Like many research chemicals, 2-Fluorodeschloroketamine has also gained popularity among certain individuals for recreational purposes. It is sometimes used recreationally for its dissociative effects, offering a unique and altered state of consciousness.

Safety considerations:

2-FDCK is a research compound and should not be consumed by humans. It is imperative to underscore that the recreational use of 2-FDCK is not without risk. Since the safety profile and long-term consequences of 2-Fluorodeschloroketamine are yet unclear, using it should be done cautiously.

Legality and Regulation (Legal status of 2-Fluorodeschloroketamine)

The legal standing of 2-FDCK differs between nations. It may be categorized as a controlled substance in some areas and as a legal gray area in others. Before pondering its application, it is crucial to learn about and comprehend the laws and rules about 2-Fluorodeschloroketamine in your particular region. 4F MPH

Is 2-FDCK safe to use?

A1: The safety of 2-FDCK depends on various factors, including dosage, frequency of use, and individual health. It is important to approach any psychoactive substance with caution and to be aware of the potential risks and side effects.

How is 2-FDCK typically consumed?

2-Fluorodeschloroketamine can be consumed through various routes, including oral ingestion, nasal insufflation (snorting), and intravenous injection. Each route of administration may result in different onset times and intensities of effects.

Can 2-FDCK be detected in drug tests?

Yes, 2-FDCK can be detected in certain drug tests. It is important to be aware of the potential consequences and legal implications of its presence in your system.

The long-term effects of 2-FDCK  or MDA-19 use are not yet fully understood, as research on this substance is still limited. However, like other dissociative drugs, prolonged and excessive use of 2-FDCK may lead to cognitive impairments, memory problems, and potential damage to the urinary system. It is important to use this substance responsibly and in moderation.

Combining 2-FDCK with other substances, especially depressants like alcohol or benzodiazepines, can increase the risk of adverse effects, including respiratory depression and overdose. It is crucial to exercise caution and avoid mixing substances without proper knowledge and guidance.

How 2-FDCK Differs from Ketamine

At first glance, 2-FDCK seems like ketamine’s twin. Both belong to the arylcyclohexylamine class, which includes substances known for their dissociative effects—think distorted perceptions of sight and sound, feelings of detachment, and, at higher doses, “k-hole” experiences. But minor structural changes can lead to major differences:

Factor	Ketamine	2-FDCK
Potency	1x (baseline)	~0.5–0.7x (less potent)
Duration	45–90 minutes	60–120 minutes
Legal Status (U.S.)	Schedule III	Not federally controlled*

Sources: Comparative data from Psychopharmacology Journal studies on arylcyclohexylamines.
*Legal status varies globally; always verify local laws.

The added fluorine atom in 2-FDCK likely slows its metabolism, extending its effects. However, its lower potency means users often take higher doses to achieve similar results—a gamble with unknown long-term consequences.

Effects: Euphoria, Risks, and Unanswered Questions

User reports on platforms like Erowid describe 2-FDCK’s effects as “smoother” and “less chaotic” than ketamine, with a gradual onset and prolonged dissociation. But these anecdotes aren’t peer-reviewed, and the lack of clinical studies leaves critical gaps. Potential risks include:

• Bladder toxicity: Chronic ketamine use can damage the urinary tract; it’s unclear if 2-FDCK shares this risk.
• Cognitive impairment: Dissociatives may affect memory and attention, especially with frequent use.
• Addiction potential: Like ketamine, 2-FDCK could lead to psychological dependence.

A 2021 review in Drug Testing and Analysis flagged 2-FDCK as part of a “worrisome trend” of NPS proliferation, urging stricter international controls.

Dissociative and Subjective Effects

At lower doses, users report effects resembling those of alcohol intoxication—an easing of inhibitions and mild euphoria. In contrast, higher doses may induce a state colloquially known as a “k-hole,” a term describing profound dissociation and detachment from reality. The variation in dosage and onset is highly dose-dependent, making it crucial for researchers and clinicians to approach studies on 2-FDCK with meticulous dosing strategies.

Safety and Toxicity Considerations

While 2-FDCK is still under investigation, early toxicological analyses indicate that it has a safety profile similar to ketamine when used in controlled environments. However, potential risks include adverse cardiovascular effects such as increased heart rate and blood pressure. For more detailed toxicological data, refer to the Forensic Science International study that analyzed urinary samples from patients exposed to 2-FDCK.

Legal and Regulatory Landscape

The legal status of 2-FDCK varies widely across jurisdictions. In the U.S., 2-FDCK isn’t explicitly banned at the federal level, but it could fall under the Federal Analogue Act if sold for human consumption. The Drug Enforcement Administration (DEA) monitors its distribution closely, and several states have moved to regulate it independently.

Internationally, countries like the U.K. and Sweden classify it as a controlled substance. In many European nations, it is subject to strict controls. For instance, in Italy and Sweden, 2-FDCK is classified as an illegal substance, while in countries like Canada and Belgium, it falls under broader bans on novel psychoactive substances. The UNODC database offers updated details on international scheduling proposals that might affect 2-FDCK in the near future.

Regional Legal Status Overview

• Europe: In several European countries, 2-FDCK is regulated under national laws designed to control new psychoactive substances.
• North America: Although not scheduled under the Controlled Substances Act in the United States, its status remains ambiguous due to structural similarities with ketamine.
• Asia: Countries like Japan and Singapore have strict controls in place, making the substance illegal.

 

Harm Reduction: Navigating Uncertain Terrain

If you’re experimenting with 2-FDCK (or any NPS), harm reduction is critical:

1. Test your substances: Use reagent kits from organizations like DanceSafe to verify purity.
2. Start low, go slow: Dose cautiously to gauge individual tolerance.
3. Avoid mixing: Combining dissociatives with alcohol or opioids can be deadly.

This patchwork of regulations underscores the need for researchers to remain informed about local and international legal frameworks before engaging in any work with 2-FDCK.

What distinguishes 2-FDCK from ketamine?

While both drugs share structural similarities, 2-FDCK differs primarily due to the substitution of a chlorine atom with fluorine. This small change can affect the compound’s metabolism and potency. For a detailed comparison, check the Journal of Pharmaceutical and Biomedical Analysis which reviews similar ketamine analogues.

How long do the effects of 2-FDCK last?

The duration of 2-FDCK effects varies by the route of administration. When taken orally, the effects can last between 2.5 and 5 hours, whereas insufflation results in a shorter duration of 1.5 to 3 hours. This variability is crucial for dosing considerations in both research and clinical studies.

 Is 2-FDCK safe for use in research?

Preliminary studies suggest that when used responsibly in controlled settings, 2-FDCK exhibits a safety profile comparable to ketamine. However, as with any research chemical, it is imperative to follow strict protocols to minimize risks. Detailed safety assessments can be found in publications on Forensic Toxicology.

What are the potential therapeutic applications of 2-FDCK?

Although 2-FDCK is primarily used for research purposes, its pharmacological properties have spurred interest in potential therapeutic applications, especially in the field of mental health. Its NMDA antagonism is similar to ketamine, which is already being explored for rapid-acting antidepressant effects. Further research in this area is essential before any clinical applications can be confirmed.

Where can researchers source high-quality 2-FDCK?

Reputable suppliers like Aimimichem offer high-quality research chemicals, including 2-FDCK, ensuring compliance with safety and legal standards. It is crucial to purchase from verified sources to guarantee purity and consistency.

Can 2-FDCK treat depression like ketamine?
No clinical trials support this. Ketamine’s antidepressant effects are dose- and setting-specific; self-medicating is risky.

How does 2-FDCK compare to DCK (deschloroketamine)?
DCK is another ketamine analogue but is typically more potent and longer-lasting than 2-FDCK.

 What’s the safest way to use 2-FDCK?
Avoid frequent use, stay hydrated, and never use alone.

 Are there drug tests for 2-FDCK?
Standard drug tests don’t screen for it, but specialized panels might.

Strategic Calls to Action

If you’re a researcher or a forensic scientist keen on exploring the nuances of dissociative agents, consider integrating 2 FDCK into your studies. Stay ahead of regulatory changes by following updates from the European Commission and international agencies like the UNODC. Join our community of experts to share insights, ask questions, and discuss safe handling practices for novel research chemicals.

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