Buy 2-FDCK Online

What is 2-Fluorodeschloroketamine? 🧪 | 2-FDCK for Sale | Buy 2-FDCK Online

2-Fluorodeschloroketamine, commonly known as 2-FDCK, represents a fascinating development in the world of research chemicals. As a structural analogue of the well-known dissociative anesthetic ketamine, 2-FDCK has garnered significant attention from researchers and enthusiasts alike. At Newchemicalz.com, we pride ourselves on offering high-quality 2-FDCK for sale to qualified researchers and institutions across the United Kingdom, United States, Germany, Australia, and Asia.

2-Fluorodeschloroketamine belongs to the arylcyclohexylamine class of compounds, sharing a similar chemical backbone with ketamine but with a crucial difference: the chlorine atom in ketamine is replaced by a fluorine atom in 2-FDCK. This seemingly minor modification results in distinct pharmacological properties that make it a subject of intense scientific interest.

When you buy 2-FDCK online from our platform, you are accessing a compound that has been synthesised to the highest standards of purity and consistency. Our commitment to excellence ensures that researchers receive materials suitable for rigorous scientific investigation.

What is 2-Fluorodeschloroketamine? Understanding the Basics 📚

Chemical Structure and Properties

2-Fluorodeschloroketamine (IUPAC name: 2-(2-fluorophenyl)-2-(methylamino)cyclohexan-1-one) is a dissociative anaesthetic related to ketamine. Its molecular formula is C₁₃H₁₆FNO, with a molar mass of 221.275 g/mol. The compound features a cyclohexylamine unit with an aryl group attached to the same carbon as the amine, specifically an o-fluorophenyl group as the aryl substituent.

The chemical structure of 2-FDCK differs from ketamine only in that there is a fluorine atom attached to the phenyl group instead of chlorine. This modification significantly influences the compound’s properties, including its lipophilicity, metabolism, and duration of action.

Historical Background

The synthesis of 2-FDCK was first described in a 2013 paper as part of a larger effort to develop new anaesthetic drugs based on ketamine and its analogues. Since then, it has emerged as a research chemical of interest, with the first documented detection by government authorities reported in Spain in 2016.

According to the World Health Organization, 2-FDCK has been detected in products or biological samples in at least 11 countries, including Australia, Austria, Canada, China, Denmark, Finland, France, Italy, the Netherlands, the United Kingdom, and the USA.

Pharmacological Profile

Research suggests that 2-FDCK acts primarily as an NMDA receptor antagonist, similar to ketamine. However, due to the fluorine substitution, the molecule is more polar than ketamine, which may influence its binding to proteins, including the NMDA receptor.

Studies have shown that 2-FDCK demonstrates stronger docking to CYP2B6 in simulations, as well as a slower metabolism rate than ketamine. The lipophilicity is observed to be lower for 2-FDCK than for ketamine, and in vitro to in vivo extrapolation predicts that 2-FDCK shows a lower intrinsic hepatic clearance than ketamine. Both of these characteristics suggest that the effects of 2-FDCK last longer than those of ketamine.

The Science Behind 2-FDCK: Mechanisms of Action 🧠

NMDA Receptor Antagonism

The primary mechanism of action for 2-FDCK appears to be NMDA receptor antagonism. NMDA receptors allow for electrical signals to pass between neurons in the brain and spinal column. For the signals to pass, the receptor must be open. Dissociatives like 2-FDCK close the NMDA receptors by blocking them, leading to disconnection of neurons, loss of feeling, difficulty moving, and eventually, dissociative states.

Metabolism and Pharmacokinetics

The metabolism of 2-FDCK is analogous to that of ketamine. The enzymes CYP2B6 and CYP3A4, the latter to a lesser extent, metabolise 2-FDCK to Nor-2FDCK via N-demethylation. This is further metabolised either to dehydronor-2FDCK by CYP2B6 or to hydroxynor-2FDCK by CYP2A6 and CYP2B6.

For general halogen substitutions of ketamine, docking strength for CYP2B6 follows the pattern H < Br < Cl < F. The parameter of internal clearance follows the pattern Br > Cl > F > H. Lastly, Km (Michaelis constant) follows the pattern of Br < Cl < F < H, and as such, the in-vitro metabolism rate follows the inverse pattern, namely Br > Cl > F > H.

Duration and Onset of Effects

Based on user reports and pharmacological studies, the effects of 2-FDCK typically last longer than those of ketamine. The duration can be summarised as follows:

• Total duration: 2.5 – 5.0 hours
• Onset: 15 – 50 minutes
• Peak: 50 – 100 minutes
• After effects: 3 – 8 hours

This extended duration makes 2-FDCK particularly interesting for researchers studying the prolonged effects of dissociative compounds on the central nervous system.

2-FDCK for Sale: Product Specifications and Quality Assurance 🛡️

Purity and Composition

At Newchemicalz.com, when you order 2-FDCK, you receive a product with guaranteed purity levels. Our 2-FDCK is typically available as a white crystalline powder or crystal form, with purity exceeding 98% as verified by independent laboratory analysis.

Packaging and Storage

Our 2-FDCK is packaged in airtight, light-resistant containers to maintain stability and prevent degradation. We recommend storing the product in a cool, dry place away from direct sunlight to preserve its integrity over time.

Batch Testing and Documentation

Each batch of our 2-Fluorodeschloroketamine undergoes rigorous quality control testing, including:

• High-performance liquid chromatography (HPLC) for purity assessment
• Gas chromatography-mass spectrometry (GC-MS) for identity confirmation
• Nuclear magnetic resonance (NMR) spectroscopy for structural verification
• Heavy metal screening to ensure safety

Documentation, including certificates of analysis (CoA) is provided with every order, ensuring transparency and traceability.

Comparative Analysis: 2-FDCK vs. Ketamine ⚖️

Chemical Differences

Pharmacological Differences

Research indicates that while both compounds act as NMDA receptor antagonists, 2-FDCK demonstrates some unique properties:

1. Longer duration of action: Due to slower metabolism, 2-FDCK effects last longer than ketamine
2. Different metabolic pathway: The fluorine substitution alters how the compound is processed in the body
3. Varied receptor affinity: The structural change may influence binding affinity to various receptors

Subjective Effects Comparison

User reports suggest that 2-FDCK produces effects similar to ketamine but with some notable differences:

• Smoother onset: Many users report a more gradual onset compared to ketamine
• Less intense peak: The peak effects may be less intense but more sustained
• Extended afterglow: The after-effects tend to last longer with 2-FDCK
• Different body load: Some users report less physical discomfort with 2-FDCK

Legal Status of 2-FDCK Across Different Countries 🌍

International Control Status

As of October 2023, the ECDD recommended that 2-FDCK be added to Schedule II of the Convention on Psychotropic Substances of 1971. However, it is not yet under international control.

National Regulations

The legal status of 2-FDCK varies significantly by country:

United Kingdom 🇬🇧

In the UK, 2-FDCK is covered under the Psychoactive Substances Act 2016, making it illegal to produce, supply, or import for human consumption.

United States 🇺🇸

2-FDCK is not currently controlled at the federal level in the US, though it may be subject to the Federal Analogue Act in certain contexts. Some states have implemented their own controls.

Germany 🇩🇪

Germany regulates 2-FDCK under the New Psychoactive Substances Act (NpSG), making it subject to strict controls.

Australia 🇦🇺

Australia has implemented strict controls on 2-FDCK, classifying it as a controlled substance.

Asian Countries 🌏

Various Asian countries have different approaches to 2-FDCK regulation, with some implementing strict controls while others have yet to address it specifically.

Implications for Researchers

Researchers must be aware of and comply with all relevant regulations in their jurisdiction when working with 2-FDCK. Proper documentation and authorisation may be required depending on the intended use and location.

Research Applications and Potential Uses 🔬

Neurological Research

2-FDCK has shown promise in various neurological research applications:

1. Depression studies: Similar to ketamine, 2-FDCK may have antidepressant properties worth investigating
2. Consciousness research: Its dissociative effects make it valuable for studying altered states of consciousness
3. Neuroplasticity investigations: Research into how dissociative compounds affect neural connections

Pharmacological Studies

The unique properties of 2-FDCK make it an interesting subject for pharmacological research:

• Metabolism studies: Understanding how structural changes affect drug metabolism
• Receptor binding research: Investigating how fluorine substitution affects receptor affinity
• Duration of action studies: Exploring factors that influence the longevity of drug effects

Forensic Applications

2-FDCK has become important in forensic science:

• Detection methods: Developing new techniques for identifying novel psychoactive substances
• Metabolite identification: Understanding how 2-FDCK breaks down in the body
• Toxicological studies: Assessing the effects and risks of 2-FDCK consumption

Safety Considerations and Harm Reduction 🛡️

Known Risks

Research has identified several potential risks associated with 2-FDCK:

1. Impaired consciousness: High doses can lead to significant dissociation and loss of awareness
2. Cardiovascular effects: May include hypertension and tachycardia
3. Neurological effects: Can cause agitation, abnormal behaviour, and hallucinations
4. Dependence potential: Studies suggest similar abuse potential to ketamine

Harm Reduction Strategies

For researchers working with 2-FDCK, the following harm reduction strategies are recommended:

• Start with low doses: Due to individual variations in sensitivity
• Proper laboratory safety: Use appropriate personal protective equipment
• Controlled environments: Conduct research in controlled, supervised settings
• Emergency preparedness: Have protocols in place for adverse reactions

Storage and Handling

Proper storage and handling of 2-FDCK are essential for safety:

• Temperature control: Store in a cool, dry place
• Moisture protection: Keep away from humidity
• Light sensitivity: Protect from direct sunlight
• Containment: Use appropriate containers to prevent accidental exposure

How to Buy 2-FDCK Online: A Guide for Researchers 🛒

Choosing a Reputable Supplier

When looking to buy 2-FDCK online, consider the following factors:

1. Reputation: Look for suppliers with established track records
2. Quality assurance: Ensure proper testing and documentation
3. Customer service: Responsive and knowledgeable support
4. Shipping reliability: Discreet and reliable delivery options
5. Payment security: Secure transaction processing

The Ordering Process

Ordering 2-FDCK from Newchemicalz.com is straightforward:

1. Account creation: Register for a research account
2. Verification: Complete necessary verification steps
3. Product selection: Choose the desired quantity and form
4. Checkout: Complete the secure payment process
5. Shipping: Receive tracking information for your order

Payment Options

We offer various payment options for purchasing research chemicals:

• Cryptocurrency: Bitcoin and other major cryptocurrencies
• Bank transfers: Secure wire transfer options
• Credit cards: Major credit and debit cards (where permitted)

Shipping and Delivery

Our shipping process ensures:

• Discreet packaging: Plain, unmarked packaging for privacy
• Temperature control: Proper packaging to maintain product integrity
• Tracking: Full tracking information for all orders
• Insurance: Coverage for loss or damage during transit

Frequently Asked Questions About 2-FDCK ❓

What is 2-Fluorodeschloroketamine used for in research?

2-Fluorodeschloroketamine is primarily used in neurological and pharmacological research. Scientists study its effects on NMDA receptors, its potential applications in depression research, and its unique metabolic properties compared to ketamine. It also serves as a reference standard in forensic laboratories for the identification of novel psychoactive substances.

Is 2-FDCK legal to buy for research purposes?

The legality of 2-FDCK varies by country and jurisdiction. In some places, it may be legal to purchase for legitimate research purposes with proper authorisation, while in others it may be strictly controlled. Researchers must verify and comply with all local regulations before acquiring or working with 2-FDCK.

How does 2-FDCK compare to ketamine in terms of effects?

2-FDCK produces effects similar to ketamine but with some key differences. Users often report that 2-FDCK has a longer duration of action, a smoother onset, and less intense peak effects compared to ketamine. The after-effects also tend to last longer with 2-FDCK. These differences are attributed to the fluorine substitution, which affects metabolism and receptor binding.

What are the potential risks of working with 2-FDCK in a laboratory setting?

The main risks when working with 2-FDCK include accidental exposure, which could lead to dissociation, impaired consciousness, and cardiovascular effects. Proper laboratory safety protocols, including the use of personal protective equipment, adequate ventilation, and emergency procedures, are essential to mitigate these risks.

Where can I find reliable information about 2-FDCK research?

Reliable information about 2-FDCK can be found in peer-reviewed scientific journals, official government publications (such as the WHO critical review report), and reputable scientific databases like PubMed. Always verify information from multiple credible sources and consult with experienced researchers in the field.

Key Takeaways: Understanding 2-FDCK 🎯

• 2-Fluorodeschloroketamine (2-FDCK) is a structural analogue of ketamine with a fluorine atom replacing the chlorine atom
• The compound acts primarily as an NMDA receptor antagonist, producing dissociative effects similar to ketamine
• 2-FDCK typically has a longer duration of action than ketamine due to slower metabolism
• Legal status varies by country, with some nations implementing strict controls while others have yet to address it specifically
• When you buy 2-FDCK online from reputable suppliers like Newchemicalz.com, you receive high-quality material suitable for research purposes
• Proper safety protocols and harm reduction strategies are essential when working with 2-FDCK in research settings
• The compound shows promise for various research applications, including neurological studies and forensic science

Conclusion: The Future of 2-FDCK Research 🔮

As research into novel psychoactive substances continues to evolve, 2-Fluorodeschloroketamine remains a compound of significant interest to the scientific community. Its unique properties and potential applications make it valuable for various research endeavours, from understanding consciousness to developing new therapeutic approaches.

At Newchemicalz.com, we are committed to supporting legitimate research by providing high-quality 2-FDCK for sale to qualified researchers and institutions. Our rigorous quality control processes and commitment to excellence ensure that when you buy 2-FDCK online from us, you receive materials that meet the highest standards of purity and consistency.

We encourage researchers to explore the potential of this fascinating compound while adhering to all relevant regulations and safety protocols. As our understanding of 2-FDCK continues to grow, so too will its potential contributions to science and medicine.

For more information about our research chemicals and to explore our full range of products, visit our research chemicals collection or check out our blog for the latest updates and insights in the field.

Remember to always conduct research responsibly and in compliance with all applicable laws and regulations. The future of scientific discovery depends on the integrity and diligence of today’s researchers.